Structure of PDB 4xl1 Chain A

Receptor sequence
>4xl1A (length=115) Species: 10116 (Rattus norvegicus) [Search protein sequence]
DECALGANPCEHAGKCLNTLGSFECQCLQGYTGPRCEIDVNECISNPCQN
DATCLDQIGEFQCICMPGYEGVYCEINTDECASSPCLHNGRCVDKINEFL
CQCPKGFSGHLCQSG
3D structure
PDB4xl1 Structural biology. Structural basis for Notch1 engagement of Delta-like 4.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 BGC A E455 S458 F474 E42 S45 F61
BS02 FUC A D464 T466 D51 T53
BS03 BGC A E493 S496 E80 S83
BS04 CA A D452 V453 E455 D469 Q470 D39 V40 E42 D56 Q57
BS05 CA A N490 T491 E493 D507 K508 N77 T78 E80 D94 K95
BS06 CA A N431 T432 L433 G434 S435 N18 T19 L20 G21 S22
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:4xl1, PDBe:4xl1, PDBj:4xl1
PDBsum4xl1
PubMed25700513
UniProtQ07008|NOTC1_RAT Neurogenic locus notch homolog protein 1 (Gene Name=Notch1)

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