Structure of PDB 4xkn Chain A

Receptor sequence
>4xknA (length=465) Species: 1458279 (Staphylococcus aureus USA300-ISMMS1) [Search protein sequence]
GKDLNISLPLKTKSIAPYETDVPVKIGAAESLFKTNDQGKIEKALVKSYH
QPNDTTLDIELKDNIKFQNGQKLTAEKVKSSLENSMKKSDLVKYSLPISS
ITAKGQKLTIKTNSAYPELVSELANPFMAIYDTDAKSDVNQTPVGTGPYQ
IKDYKQSRKISLSNFKDYWQGKPKLDHITVTYQEDGNNRVRNLESQKDDL
ITDVPVNKVQDIENNQNLKVSKESGFRTSLLMYNHTNKKMTKSVREALDH
IIDRQGIADHIYQGYAKPATSPFNDKIPYIKEPKLTKQNIEQAKMLLAKD
GYTKEHPLKIKLITYDGRPELSKIAQVLQSDAKKANIEIDIKSVDDIEGY
LKDRSAWDATMYSFGTIPRGDTGYFFNQAYKKDGAINKGDYNNSNVDDLI
NQLNHTVDVKERHNISNDIIKLSSRDVPNSYIAYNDQIVAANSKVKNYKV
TPEGIYLIDYRTTIE
3D structure
PDB4xkn Novel insights into nickel import in Staphylococcus aureus: the positive role of free histidine and structural characterization of a new thiazolidine-type nickel chelator.
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HIS A L17 Y322 R325 I354 E355 Y369 S370 L10 Y315 R318 I347 E348 Y362 S363
BS02 HIS A R234 F371 G372 R227 F364 G365
Gene Ontology
Molecular Function
GO:1904680 peptide transmembrane transporter activity
Biological Process
GO:0015675 nickel cation transport
GO:0015833 peptide transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space
GO:0043190 ATP-binding cassette (ABC) transporter complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4xkn, PDBe:4xkn, PDBj:4xkn
PDBsum4xkn
PubMed25611161
UniProtQ2G2P5|NIKA_STAA8 Nickel-binding protein NikA (Gene Name=nikA)

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