Structure of PDB 4xkf Chain A

Receptor sequence
>4xkfA (length=329) Species: 119212 (H6N1 subtype) [Search protein sequence]
PGDKICIGYHANNSTTQVDTLLEKNVTVTHSVELLENQKEKRFCKIMNKA
PLDLKDCTIEGWILGNPKCDLLLGDQSWSYIVERPNAQNGICYPGVLNEL
EELKAFIGSGERVERFEMFPKSTWAGVDTSRGVTNACPSYTIDSSFYRNL
VWIVKTDSATYPVIKGTYNNTGTQPILYFWGVHHPLDTTVQDNLYGSGDK
YVRMGTESMNFAKSPEIAARPAVNGQRSRIDYYWSVLRPGETLNVESNGN
LIAPWYAYKFVSTNKGAVFKSDLPIENCDATCQTITGVLRTNKTFQNVSP
LWIGECPKYVKSESLRLATGLRNVPQIAT
3D structure
PDB4xkf Structure and Receptor Binding of the Hemagglutinin from a Human H6N1 Influenza Virus.
ChainA
Resolution2.446 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SIA A Y98 V135 T136 N137 W153 H183 L194 Q226 S228 Y93 V133 T134 N135 W152 H183 L194 Q226 S228
Gene Ontology
Molecular Function
GO:0046789 host cell surface receptor binding
Biological Process
GO:0019062 virion attachment to host cell
GO:0019064 fusion of virus membrane with host plasma membrane
GO:0039654 fusion of virus membrane with host endosome membrane
GO:0046718 symbiont entry into host cell
GO:0075512 clathrin-dependent endocytosis of virus by host cell
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016324 apical plasma membrane
GO:0019031 viral envelope
GO:0020002 host cell plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4xkf, PDBe:4xkf, PDBj:4xkf
PDBsum4xkf
PubMed25766295
UniProtA0A0J9X268

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