Structure of PDB 4xjj Chain A

Receptor sequence
>4xjjA (length=105) Species: 9606 (Homo sapiens) [Search protein sequence]
ALCKFCDVRFSTCDNQKSCMSNCSITSICEKPQEVCVAVWRKNDENITLE
TVCHDPKLPYHDFILEDAASPTCIMKEKKKPGETFFMCSCSSDECNDNII
FSEEY
3D structure
PDB4xjj Extracellular domain of type II Transforming Growth Factor Beta receptor in complex with 2-(2-Hydroxyethyl)NDSB-201
ChainA
Resolution1.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.30: receptor protein serine/threonine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 41D A C38 Q41 W65 F111 F126 C13 Q16 W40 F86 F101
Gene Ontology
Molecular Function
GO:0005026 transforming growth factor beta receptor activity, type II
GO:0005524 ATP binding
GO:0046872 metal ion binding
Biological Process
GO:0006468 protein phosphorylation
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4xjj, PDBe:4xjj, PDBj:4xjj
PDBsum4xjj
PubMed
UniProtP37173|TGFR2_HUMAN TGF-beta receptor type-2 (Gene Name=TGFBR2)

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