Structure of PDB 4xj5 Chain A

Receptor sequence
>4xj5A (length=367) Species: 243277 (Vibrio cholerae O1 biovar El Tor str. N16961) [Search protein sequence]
RMTWNFHQYYTNRNDGLMGKLVLTDEEKNNLKALRKIIRLRTRDVFEEAK
GIAKAVKKSALTFEIIQEKVSTTQIKHLSDSEQREVAKLIYEMDDDARDE
FLGLTPRFWTQGSFQYDTLNRPFQPGQEMDIDDGTYMPMPIKIGHSLLIL
LVDASLKSLVAENHGWKFEAKQTCGRIKIEAEKTHIDVPMYAIPKGSENV
NLALREGDRKWINSDPKIVEDWFNDSCIRIGKHLRKVCRFMKAWRDAQWD
VGGPSSISLMAATVNILDSVAHDASDLGETMKIIAKHLPSEFARGVESPD
STDEKPLFPPSYKHGPREMDIMSKLERLPEILSSAESADSKSEALKKINM
AFGNRVTNSELIVLAKA
3D structure
PDB4xj5 Structural Basis for the Catalytic Mechanism of DncV, Bacterial Homolog of Cyclic GMP-AMP Synthase
ChainA
Resolution1.552 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.7.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D131 D133 D130 D132
BS02 MG A D131 D133 D193 D130 D132 D187
BS03 GH3 A Q112 D133 K177 T179 C180 D193 Y197 S259 Q111 D132 K171 T173 C174 D187 Y191 S214
BS04 GH3 A Q112 G113 S114 Y117 D131 D133 K287 S301 I302 D348 Q111 G112 S113 Y116 D130 D132 K242 S256 I257 D303
Gene Ontology
Molecular Function
GO:0140701 3',3'-cyclic GMP-AMP synthase activity

View graph for
Molecular Function
External links
PDB RCSB:4xj5, PDBe:4xj5, PDBj:4xj5
PDBsum4xj5
PubMed25865248
UniProtQ9KVG7|DNCV_VIBCH Cyclic GMP-AMP synthase (Gene Name=dncV)

[Back to BioLiP]