Structure of PDB 4xhz Chain A

Receptor sequence
>4xhzA (length=333) Species: 9606 (Homo sapiens) [Search protein sequence]
SPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYRIRSPEVKHFF
ALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVI
VKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRY
RVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPV
MSSSATVKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISAAAINQ
SIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVV
LANLRVPSKSNTAKVYIEIQDENNHPPVFLEHH
3D structure
PDB4xhz An elastic element in the protocadherin-15 tip link of the inner ear.
ChainA
Resolution2.803 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A N899 Y901 D931 D933 A939 D989 N105 Y107 D137 D139 A145 D195
BS02 CA A E809 E862 D897 M898 D900 E15 E68 D103 M104 D106
BS03 CA A E809 D860 E862 D900 E15 D66 E68 D106
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0098609 cell-cell adhesion
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4xhz, PDBe:4xhz, PDBj:4xhz
PDBsum4xhz
PubMed27857071
UniProtQ96QU1|PCD15_HUMAN Protocadherin-15 (Gene Name=PCDH15)

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