Structure of PDB 4xgl Chain A

Receptor sequence
>4xglA (length=342) Species: 9606 (Homo sapiens) [Search protein sequence]
TLEPRGYSLLIRGLIHSDRWREALLLLEDIKKVITPSKKNYNDCIQGALL
HQDVNTAWNLYQELLGHDIVPMLETLKAFFDFGKDIKDDNYSNKLLDILS
YLRNNQLYPGESFAHSIKTWFESVPGKQWKGQFTTVRKSGQCSGCGKTIE
SIQLSPEEYECLKGKIMRDVITTPQELKRFENFIKSRPPFDVVIDGLNVA
KMESQLLLNVVSQLAKRNLRLLVLGRKHMLRDEMEEVQKQASCFFADDID
DPFLLYATLHSGNHCRFITRDLMDAKTQRLFFKWQQGHQLAIVNSKLTFQ
RILSYDTVVQTTGDSWHIPYDEDLVERCSCEVPTKWLCLHQK
3D structure
PDB4xgl Structure of the nuclease subunit of human mitochondrial RNase P.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.26.5: ribonuclease P.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C348 C351 H557 C578 C142 C145 H317 C338
Gene Ontology
Biological Process
GO:0008033 tRNA processing
Cellular Component
GO:0005739 mitochondrion

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Biological Process
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Cellular Component
External links
PDB RCSB:4xgl, PDBe:4xgl, PDBj:4xgl
PDBsum4xgl
PubMed25953853
UniProtO15091|MRPP3_HUMAN Mitochondrial ribonuclease P catalytic subunit (Gene Name=PRORP)

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