Structure of PDB 4xf7 Chain A

Receptor sequence
>4xf7A (length=273) Species: 69014 (Thermococcus kodakarensis KOD1) [Search protein sequence]
MKCLVVGHVVRDIVKKGNKVLERLGGGAYYSALALSRFCDVEILTSFSNL
PEEWIKELESMAKLQVVPSETTTTYELTYLDGNRRRLKLLERASPIEELP
DGEYDVLLMNPVAREVPPALVTSALKKFPFVAVDIQGFIRSSSPGEIQYQ
PIDGSFLKGVKILHADLGEYQYLQGFSPEFVDVLLLSNGPEPGKAFLHGR
EYTFEPVHVGVDESTGAGDVFLGAFTGFYSQCPFVQALKRAAAFTALFLK
NRSVDFSMDDVNELAMKVEVKRV
3D structure
PDB4xf7 Crystal Structure and Product Analysis of an Archaeal myo-Inositol Kinase Reveal Substrate Recognition Mode and 3-OH Phosphorylation
ChainA
Resolution1.93 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.64: inositol 3-kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 INS A D12 G25 G26 Y30 Y75 Q136 R140 D219 D12 G25 G26 Y30 Y75 Q136 R140 D219
BS02 ACP A N83 R85 D166 S187 G189 P190 F204 P206 S214 A217 G218 T245 L249 N83 R85 D166 S187 G189 P190 F204 P206 S214 A217 G218 T245 L249
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016301 kinase activity
Biological Process
GO:0016310 phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:4xf7, PDBe:4xf7, PDBj:4xf7
PDBsum4xf7
PubMed25972008
UniProtQ5JDA3

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