Structure of PDB 4xba Chain A

Receptor sequence
>4xbaA (length=199) Species: 284812 (Schizosaccharomyces pombe 972h-) [Search protein sequence]
SFRDNLKVYIESPESYKNVIYYDDDVVLVRDMFPKSKMHLLLMTRDPHLT
HVHPLEIMMKHRSLVEKLVSYVQGDLSGLIFDEARNCLSQQLTNEALCNY
IKVGFHAGPSMNNLHLHIMTLDHVSPSLKNSAHYISFTSPFFVKIDTPTS
NLPTRGTLTSLFQEDLKCWRCGETFGRHFTKLKAHLQEEYDDWLDKSVS
3D structure
PDB4xba DNA3'pp5'G de-capping activity of aprataxin: effect of cap nucleoside analogs and structural basis for guanosine recognition.
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.71: adenosine-5'-diphospho-5'-[DNA] diphosphatase.
3.6.1.72: DNA-3'-diphospho-5'-guanosine diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GMP A Y41 D63 M64 F65 M143 H147 Y9 D31 M32 F33 M111 H115
BS02 ZN A C200 C203 H217 E221 C168 C171 H185 E189
Gene Ontology
Molecular Function
GO:0003824 catalytic activity

View graph for
Molecular Function
External links
PDB RCSB:4xba, PDBe:4xba, PDBj:4xba
PDBsum4xba
PubMed26007660
UniProtO74859|APTX_SCHPO Aprataxin-like protein (Gene Name=hnt3)

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