Structure of PDB 4xaj Chain A

Receptor sequence
>4xajA (length=568) Species: 9606,83333 [Search protein sequence]
KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQV
AATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYN
GKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFN
LQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIK
NKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTF
KGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLG
AVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINA
ASGRQTVDEALKDAQTNAAAEFTESVCESAARLLFMSIKWAKSVPAFSTL
SLQDQLMLLEDAWRELFVLGIAQWAIPVDANTLLAVSGMNGDNTDSQRLT
LIISEIQALQEVVARFRQLRLDATEFACLKCIVTFKAVPLRSFRNAAAIA
ALQDEAQLTLNSYIHTRYPTQPVRFGKLLLLLPALRSISPSTIEEVFFKK
TIGNVPITRLLSDMYKSS
3D structure
PDB4xaj Structural basis for corepressor assembly by the orphan nuclear receptor TLX.
ChainA
Resolution3.551 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GLC A D16 K17 E113 D14 K15 E111
BS02 GLC A E46 W64 D67 R68 E155 P156 Y157 W342 E44 W62 D65 R66 E153 P154 Y155 W340
Gene Ontology
Molecular Function
GO:0015144 carbohydrate transmembrane transporter activity
Biological Process
GO:0008643 carbohydrate transport
GO:0055085 transmembrane transport

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Molecular Function

View graph for
Biological Process
External links
PDB RCSB:4xaj, PDBe:4xaj, PDBj:4xaj
PDBsum4xaj
PubMed25691470
UniProtP0AEX9|MALE_ECOLI Maltose/maltodextrin-binding periplasmic protein (Gene Name=malE);
Q9Y466

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