Structure of PDB 4xai Chain A

Receptor sequence
>4xaiA (length=565) Species: 7070,83334 [Search protein sequence]
KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQV
AATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYN
GKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFN
LQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIK
NKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTF
KGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLG
AVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINA
ASGRQTVDEALKDAQTNAAAEFPSAICESAAQLIFMNVQWVRSIPAFTCL
PLSDQLLLLEESWLDLFVLGAAQFLPLMDFSVLVEACGVLQQEPHRRDAF
LKEVADFQETLKKISQFQLDAHEFACLRAIVLFKTSFEEKTTTESAKISV
IQDDAQMRLNKHVTTTYPKQPLRFGKILLLVSSTFRTISGRTIEDLFFKK
VIRDTPIVAIISNMY
3D structure
PDB4xai Structural basis for corepressor assembly by the orphan nuclear receptor TLX.
ChainA
Resolution2.6 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A E1201 A1204 F1208 K1381 V1382 R1384 V1389 I1392 E378 A381 F385 K550 V551 R553 V558 I561
BS02 GLC A D16 K17 E113 Y157 W232 D14 K15 E111 Y155 W230
BS03 GLC A W64 D67 R68 E155 Y157 W342 W62 D65 R66 E153 Y155 W340
Gene Ontology
Molecular Function
GO:0015144 carbohydrate transmembrane transporter activity
GO:1901982 maltose binding
Biological Process
GO:0008643 carbohydrate transport
GO:0015768 maltose transport
GO:0034219 carbohydrate transmembrane transport
GO:0042956 maltodextrin transmembrane transport
GO:0055085 transmembrane transport
Cellular Component
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4xai, PDBe:4xai, PDBj:4xai
PDBsum4xai
PubMed25691470
UniProtP0AEY0|MALE_ECO57 Maltose/maltodextrin-binding periplasmic protein (Gene Name=malE);
Q9NCL0

[Back to BioLiP]