Structure of PDB 4x9v Chain A

Receptor sequence
>4x9vA (length=217) Species: 9606 (Homo sapiens) [Search protein sequence]
CHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKY
GLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNS
LMKKITLLKYFRNYMSEHLLKAGANITARLPYLRTWFRTRSAIILHLSNG
SVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELAS
RLRYARTMVDKLLSSRS
3D structure
PDB4x9v Neighbor-directed histidine N ( tau )-alkylation: A route to imidazolium-containing phosphopeptide macrocycles.
ChainA
Resolution1.429 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.11.21: polo kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A K413 W414 V415 D416 Y417 L478 Y481 Y485 L490 R516 F535 H538 K540 K42 W43 V44 D45 Y46 L107 Y110 Y114 L119 R138 F157 H160 K162
External links
PDB RCSB:4x9v, PDBe:4x9v, PDBj:4x9v
PDBsum4x9v
PubMed26152807
UniProtP53350|PLK1_HUMAN Serine/threonine-protein kinase PLK1 (Gene Name=PLK1)

[Back to BioLiP]