Structure of PDB 4x8y Chain A

Receptor sequence
>4x8yA (length=112) Species: 9606 (Homo sapiens) [Search protein sequence]
SPEFDFTPAELRRFDGVQDPRILMAINGKVFDVTKGRKFYGPEGPYGVFA
GRDASRGLATFCLDKEALKDEYDDLSDLTAAQQETLSDWESQFTFKYHHV
GKLLKEGEEPTV
3D structure
PDB4x8y Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A F106 Y107 Y113 F128 C129 W156 K163 Y164 F39 Y40 Y46 F61 C62 W89 K96 Y97
External links
PDB RCSB:4x8y, PDBe:4x8y, PDBj:4x8y
PDBsum4x8y
PubMed26988023
UniProtO00264|PGRC1_HUMAN Membrane-associated progesterone receptor component 1 (Gene Name=PGRMC1)

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