Structure of PDB 4x8n Chain A

Receptor sequence
>4x8nA (length=176) Species: 9606 (Homo sapiens) [Search protein sequence]
RVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDE
MPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSG
YGQGDVLGFYINLPEGSEIIFYKNGVNQGVAYKDIFEGVYFPAISLYKSC
TVSINFGPCFKYPPKDLTYRPMSDMG
3D structure
PDB4x8n A phosphorylation switch on RbBP5 regulates histone H3 Lys4 methylation.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A G312 Y313 R343 P356 R367 F374 S377 Y475 G27 Y28 R58 P71 R82 F89 S92 Y147
Gene Ontology
Cellular Component
GO:0048188 Set1C/COMPASS complex

View graph for
Cellular Component
External links
PDB RCSB:4x8n, PDBe:4x8n, PDBj:4x8n
PDBsum4x8n
PubMed25593305
UniProtQ9UBL3|ASH2L_HUMAN Set1/Ash2 histone methyltransferase complex subunit ASH2 (Gene Name=ASH2L)

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