Structure of PDB 4x3u Chain A

Receptor sequence
>4x3uA (length=56) Species: 10090 (Mus musculus) [Search protein sequence]
FAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEEK
EERDRA
3D structure
PDB4x3u Small-Molecule Modulators of Methyl-Lysine Binding for the CBX7 Chromodomain.
ChainA
Resolution1.63 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SVR A R20 W32 W35 Y39 S40 T41 W42 E46 H47 R10 W22 W25 Y29 S30 T31 W32 E36 H37 PDBbind-CN: -logKd/Ki=5.09,IC50=8.1uM
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:4x3u, PDBe:4x3u, PDBj:4x3u
PDBsum4x3u
PubMed25660273
UniProtQ8VDS3|CBX7_MOUSE Chromobox protein homolog 7 (Gene Name=Cbx7)

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