Structure of PDB 4x3u Chain A
Receptor sequence
>4x3uA (length=56) Species:
10090
(Mus musculus) [
Search protein sequence
]
FAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEEK
EERDRA
3D structure
PDB
4x3u
Small-Molecule Modulators of Methyl-Lysine Binding for the CBX7 Chromodomain.
Chain
A
Resolution
1.63 Å
3D
structure
[
Spin on
]
[
Spin off
]
[
Reset orientation
]
[
High quality
]
[
Low quality
]
[
White background
]
[
Black background
]
[
Download
]
[
Download structure with residue number starting from 1
]
Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
SVR
A
R20 W32 W35 Y39 S40 T41 W42 E46 H47
R10 W22 W25 Y29 S30 T31 W32 E36 H37
PDBbind-CN
: -logKd/Ki=5.09,IC50=8.1uM
Gene Ontology
Cellular Component
GO:0035102
PRC1 complex
View graph for
Cellular Component
External links
PDB
RCSB:4x3u
,
PDBe:4x3u
,
PDBj:4x3u
PDBsum
4x3u
PubMed
25660273
UniProt
Q8VDS3
|CBX7_MOUSE Chromobox protein homolog 7 (Gene Name=Cbx7)
[
Back to BioLiP
]