Structure of PDB 4x3t Chain A

Receptor sequence
>4x3tA (length=62) Species: 10090 (Mus musculus) [Search protein sequence]
HMGEQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLV
MAYEEKEERDRA
3D structure
PDB4x3t Small-Molecule Modulators of Methyl-Lysine Binding for the CBX7 Chromodomain.
ChainA
Resolution2.14 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 45E A F11 W32 W35 Y39 E43 H47 F7 W28 W31 Y35 E39 H43 MOAD: Kd=28.9uM
PDBbind-CN: -logKd/Ki=4.54,Kd=28.9uM
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:4x3t, PDBe:4x3t, PDBj:4x3t
PDBsum4x3t
PubMed25660273
UniProtQ8VDS3|CBX7_MOUSE Chromobox protein homolog 7 (Gene Name=Cbx7)

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