Structure of PDB 4x3i Chain A

Receptor sequence
>4x3iA (length=72) Species: 10116 (Rattus norvegicus) [Search protein sequence]
FPGLDTQIFEDPREFLSHLEEYLRQVGGSEEYWLSQIQNHMNGPAKKWWE
FKQGSVKNWVEFKKEFLQYSEG
3D structure
PDB4x3i Structural basis of arc binding to synaptic proteins: implications for cognitive disease.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A D210 T211 Q212 I213 F214 E215 F220 H223 L224 Y227 H245 N247 F271 D5 T6 Q7 I8 F9 E10 F15 H18 L19 Y22 H40 N42 F66
Gene Ontology
Biological Process
GO:0050804 modulation of chemical synaptic transmission
GO:2000969 positive regulation of AMPA receptor activity

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Molecular Function
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Biological Process
External links
PDB RCSB:4x3i, PDBe:4x3i, PDBj:4x3i
PDBsum4x3i
PubMed25864631
UniProtQ63053|ARC_RAT Activity-regulated cytoskeleton-associated protein (Gene Name=Arc)

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