Structure of PDB 4x3h Chain A

Receptor sequence
>4x3hA (length=79) Species: 10116 (Rattus norvegicus) [Search protein sequence]
GPLGSPEFPGLDTQIFEDPREFLSHLEEYLRQVGGSEEYWLSQIQNHMNG
PAKKWWEFKQGSVKNWVEFKKEFLQYSEG
3D structure
PDB4x3h Structural basis of arc binding to synaptic proteins: implications for cognitive disease.
ChainA
Resolution2.401 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A F206 D210 T211 Q212 I213 F214 E215 F220 H223 L224 H245 N247 F271 Y274 F8 D12 T13 Q14 I15 F16 E17 F22 H25 L26 H47 N49 F73 Y76
Gene Ontology
Biological Process
GO:0050804 modulation of chemical synaptic transmission
GO:2000969 positive regulation of AMPA receptor activity

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Molecular Function
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Biological Process
External links
PDB RCSB:4x3h, PDBe:4x3h, PDBj:4x3h
PDBsum4x3h
PubMed25864631
UniProtQ63053|ARC_RAT Activity-regulated cytoskeleton-associated protein (Gene Name=Arc)

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