Structure of PDB 4x30 Chain A

Receptor sequence
>4x30A (length=372) Species: 9606 (Homo sapiens) [Search protein sequence]
ATLYKMSSINADFAFNLYRRFTVETPDKNIFFSPVSISAALVMLSFGACC
STQTEIVETLGFNLTDTPMVEIQHGFQHLICSLNFPKKELELQIGNALFI
GKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSHVEMQTKGKVV
GLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVP
MMHQMEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSS
KTLKKWNRLLQKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSENADFS
GLTEDNGLKLSNAAHKAVLHIGEKGTEAAAVPEVELTFLHPIIQIDRSFM
LLILERSTRSILFLGKVVNPTE
3D structure
PDB4x30 Crystal structure of human Thyroxine-binding globulin complexed with thyroine at 1.55 Angstrom resolution
ChainA
Resolution1.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 T44 A S23 L246 L269 K270 N273 L376 E377 R378 R381 S7 L230 L253 K254 N257 L354 E355 R356 R359
Gene Ontology
Molecular Function
GO:0004867 serine-type endopeptidase inhibitor activity
Biological Process
GO:0070327 thyroid hormone transport
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0070062 extracellular exosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4x30, PDBe:4x30, PDBj:4x30
PDBsum4x30
PubMed
UniProtP05543|THBG_HUMAN Thyroxine-binding globulin (Gene Name=SERPINA7)

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