Structure of PDB 4wzx Chain A

Receptor sequence
>4wzxA (length=87) Species: 9606 (Homo sapiens) [Search protein sequence]
TSARDLLREMARDKPRLLAALEVASAAMAKEEAAGGEQDALDLYQHSLGE
LLLLLAAEPPGRRRELLHTEVQNLMARAEYLKEQVKM
3D structure
PDB4wzx ULK3 regulates cytokinetic abscission by phosphorylating ESCRT-III proteins.
ChainA
Resolution1.3859 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Q56 G60 L63 L66 A67 R75 H79 M86 A89 E90 K93 Q45 G49 L52 L55 A56 R64 H68 M75 A78 E79 K82
BS02 CO A H57 E61 H46 E50
External links
PDB RCSB:4wzx, PDBe:4wzx, PDBj:4wzx
PDBsum4wzx
PubMed26011858
UniProtQ6PHR2|ULK3_HUMAN Serine/threonine-protein kinase ULK3 (Gene Name=ULK3)

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