Structure of PDB 4wzw Chain A

Receptor sequence
>4wzwA (length=505) Species: 9606 (Homo sapiens) [Search protein sequence]
KTNYDIVVRAKQMWEILRRKDCDKEKRVKLMSDLQKLIQGKIKTIAFAHD
STRVIQCYIQYGNEEQRKQAFEELRDDLVELSKAKYSRNIVKKFLMYGSK
PQIAEIIRSFKGHVRKMLRHAEASAIVEYAYNDKAILEQRNMLTEELYGN
TFQLYKSADHPTLDKVLEVQPEKLELIMDEMKQILTPMAQKEAVIKHSLV
HKVFLDFFTYAPPKLRSEMIEAIREAVVYLAHTHDGARVAMHCLWHGTPK
DRKVIVKTMKTYVEKVANGQYSHLVLLAAFDCIDDTKLVKQIIISEIISS
LPSIVNDKYGRKVLLYLLSPRDPAHTVREIIEVLQKGDGNAHSKKDTEVR
RRELLESISPALLSYLQEHAQEVVLDKSACVLVSDILGSATGDVQPTMNA
IASLAATGLHPLHIAEHPAGHLVLKWLIEQDKKMKENGREGCFAKTLVEH
VGMKNLKSWASVNRGAIILSSLLQSCDLEVANKVKAALKSLIPTLEKGIE
ILLEK
3D structure
PDB4wzw A divergent Pumilio repeat protein family for pre-rRNA processing and mRNA localization.
ChainA
Resolution2.9516 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A R268 H362 V455 R140 H234 V327 PDBbind-CN: Kd=84.1nM
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:4wzw, PDBe:4wzw, PDBj:4wzw
PDBsum4wzw
PubMed25512524
UniProtQ15397|PUM3_HUMAN Pumilio homolog 3 (Gene Name=PUM3)

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