Structure of PDB 4wxq Chain A

Receptor sequence
>4wxqA (length=259) Species: 9606 (Homo sapiens) [Search protein sequence]
GCGELVWVGEPLTLRTAETITGKYGVWMRDPKPTYPYTQETTWRIDTVGT
DVRQVFEYDLISQFMQGYPSKVHILPRPLESTGAVVYSGSLYFQGAESRT
VIRYELNTETVKAEKEIPGAGYHGQFPYSWGGYTDIDLAVDEAGLWVIYS
TDEAKGAIVLSKLNPENLELEQTWETNIRKQSVANAFIICGTLYTVSSYT
SADATVNFAYDTGTGISKTLTIPFKNRYKYSSMIDYNPLEKKLFAWDNLN
MVTYDIKLS
3D structure
PDB4wxq Structural basis for misfolding in myocilin-associated glaucoma.
ChainA
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D380 N428 A429 I477 D478 D137 N185 A186 I234 D235
BS02 NA A G326 A327 D380 L381 D478 G83 A84 D137 L138 D235
External links
PDB RCSB:4wxq, PDBe:4wxq, PDBj:4wxq
PDBsum4wxq
PubMed25524706
UniProtQ99972|MYOC_HUMAN Myocilin (Gene Name=MYOC)

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