Structure of PDB 4wxl Chain A

Receptor sequence
>4wxlA (length=164) Species: 281310 (Haemophilus influenzae 86-028NP) [Search protein sequence]
ALNVLIYPDDHLKVVCEPVTEVNDAIRKIVDDMFDTMYQEKGIGLAAPQV
DILQRIITIDVEGDKQNQFVLINPEILASEGETGIEEGCLSIPGFRALVP
RKEKVTVRALDRDGKEFTLDADGLLAICIQHEIDHLNGILFVDYLSPLKR
QRIKEKLIKYKKQI
3D structure
PDB4wxl Crystal structure of a peptide deformylase from Haemophilus influenzae complex with Actinonin
ChainA
Resolution2.33 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) G46 Q51 C91 L92 H133 E134 H137
Catalytic site (residue number reindexed from 1) G44 Q49 C89 L90 H131 E132 H135
Enzyme Commision number 3.5.1.88: peptide deformylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BB2 A G44 I45 G46 Q51 E88 E89 G90 C91 L92 R98 C130 H133 E134 H137 G42 I43 G44 Q49 E86 E87 G88 C89 L90 R96 C128 H131 E132 H135
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0042586 peptide deformylase activity
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
GO:0018206 peptidyl-methionine modification

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Molecular Function
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Biological Process
External links
PDB RCSB:4wxl, PDBe:4wxl, PDBj:4wxl
PDBsum4wxl
PubMed
UniProtQ4QMV6|DEF_HAEI8 Peptide deformylase (Gene Name=def)

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