Structure of PDB 4wvj Chain A

Receptor sequence
>4wvjA (length=515) Species: 83333,93062 [Search protein sequence]
LVIWINGDKGYNGLAQVGKKFEKDTGIKVTVEHPYKLEEKFPQVAATGPD
IIFWAHDRFGGYACSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPI
AVEALSLIYNKDLLPNPPKTWEEIPALDGELKAKGKSALMFNLQEPYFTW
PLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADT
DYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPF
VGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYE
EELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVD
EALKDAQTNAGAIVTPYTIKGESMDPTLKDGERVAVNIVGYKTGLEKGNV
VVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQ
GDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDED
QIVGKVSFRFWSHPQ
3D structure
PDB4wvj Peptide binding to a bacterial signal peptidase visualized by peptide tethering and carrier-driven crystallization.
ChainA
Resolution1.95 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) G385 S387 K428 S503
Catalytic site (residue number reindexed from 1) G371 S373 K413 S488
Enzyme Commision number 3.4.21.89: signal peptidase I.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
GO:0005515 protein binding
GO:0008236 serine-type peptidase activity
GO:0015144 carbohydrate transmembrane transporter activity
GO:1901982 maltose binding
Biological Process
GO:0006465 signal peptide processing
GO:0006508 proteolysis
GO:0006974 DNA damage response
GO:0008643 carbohydrate transport
GO:0015768 maltose transport
GO:0034219 carbohydrate transmembrane transport
GO:0034289 detection of maltose stimulus
GO:0042956 maltodextrin transmembrane transport
GO:0055085 transmembrane transport
GO:0060326 cell chemotaxis
Cellular Component
GO:0016020 membrane
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space
GO:0043190 ATP-binding cassette (ABC) transporter complex
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
GO:1990060 maltose transport complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4wvj, PDBe:4wvj, PDBj:4wvj
PDBsum4wvj
PubMed26870377
UniProtP0AEX9|MALE_ECOLI Maltose/maltodextrin-binding periplasmic protein (Gene Name=malE);
Q5HHB9

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