Structure of PDB 4wsu Chain A

Receptor sequence
>4wsuA (length=325) Species: 11320 (Influenza A virus) [Search protein sequence]
SDKICIGYHANNSTTQVDTLLEKNVTVTHSVELLENQKEKRFCKIMNKAP
LDLKDCTIEGWILGNPKCDLLLGDQSWSYIVERPNAQNGICYPGVLNELE
ELKAFIGSGERVERFEMFPKSTWAGVDTSRGVTNACPSYTIDSSFYRNLV
WIVKTDSATYPVIKGTYNNTGTQPILYFWGVHHPLDTTVQDNLYGSGDKY
VRMGTESMNFAKSPEIAARPAVNGQRSRIDYYWSVLRPGETLNVESNGNL
IAPWYAYKFVSTNKKGAVFKSDLPIENCDATCQTITGVLRTNKTFQNVSP
LWIGECPKYVKSESLRLATGLRNVP
3D structure
PDB4wsu Structure and receptor binding preferences of recombinant hemagglutinins from avian and human h6 and h10 influenza a virus subtypes.
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SIA A Y91 V131 T132 N133 W150 Q224 S226 Y92 V132 T133 N134 W151 Q225 S227
Gene Ontology
Molecular Function
GO:0046789 host cell surface receptor binding
Biological Process
GO:0019062 virion attachment to host cell
GO:0019064 fusion of virus membrane with host plasma membrane
GO:0039654 fusion of virus membrane with host endosome membrane
GO:0046718 symbiont entry into host cell
GO:0075512 clathrin-dependent endocytosis of virus by host cell
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016324 apical plasma membrane
GO:0019031 viral envelope
GO:0020002 host cell plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4wsu, PDBe:4wsu, PDBj:4wsu
PDBsum4wsu
PubMed25673707
UniProtA0A0J9X246

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