Structure of PDB 4wrd Chain A

Receptor sequence
>4wrdA (length=129) Species: 93062 (Staphylococcus aureus subsp. aureus COL) [Search protein sequence]
LHKEPATLIKAIDGDTVKLMYKGQPMTFRLLLVDTPEFNEKYGPEASAFT
KKMEENAKKIEVEFDKGQRTDKYGRGLAYIYADGKMVNEALVRQGLAKVA
YVYKGNNTHEQLERKAEAQAKKEKLNIWS
3D structure
PDB4wrd Crystal structure of Staphylcoccal nulease variant Delta+PHS V66E L125E at cryogenic temperature
ChainA
Resolution1.65 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D21 R35 D40 T41 E43 R87
Catalytic site (residue number reindexed from 1) D15 R29 D34 T35 E37 R75
Enzyme Commision number 3.1.31.1: micrococcal nuclease.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA A D21 D40 T41 E43 D15 D34 T35 E37
BS02 THP A R35 K84 Y85 R87 L89 Y113 Y115 R29 K72 Y73 R75 L77 Y101 Y103
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004518 nuclease activity

View graph for
Molecular Function
External links
PDB RCSB:4wrd, PDBe:4wrd, PDBj:4wrd
PDBsum4wrd
PubMed
UniProtQ5HHM4|NUC_STAAC Thermonuclease (Gene Name=nuc)

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