Structure of PDB 4wr4 Chain A

Receptor sequence
>4wr4A (length=218) Species: 6182 (Schistosoma japonicum) [Search protein sequence]
SYSPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEGDKWRNKKFELG
LEFPNLPYYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAV
LDIRYGVSRIAYSKDFETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVT
HPDFMLYDALDVVLYMDPMCLDAFPKLVCFKKRIEAIPQIDKYLKSSKYI
AWPLQGWQATFGGGDHPP
3D structure
PDB4wr4 Protein stabilization utilizing a redefined codon
ChainA
Resolution1.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y6 L12
Catalytic site (residue number reindexed from 1) Y8 L14
Enzyme Commision number 2.5.1.18: glutathione transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSH A W7 L12 W40 K44 N53 L54 Q66 S67 W9 L14 W42 K46 N55 L56 Q68 S69
Gene Ontology
Molecular Function
GO:0004364 glutathione transferase activity
GO:0016740 transferase activity
Biological Process
GO:0006749 glutathione metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4wr4, PDBe:4wr4, PDBj:4wr4
PDBsum4wr4
PubMed25985257
UniProtP08515|GST26_SCHJA Glutathione S-transferase class-mu 26 kDa isozyme

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