Structure of PDB 4wqe Chain A

Receptor sequence

>4wqeA (length=227) Species: 572477 (Allochromatium vinosum DSM 180)

TVALTVPAAALLPDGALGESIVRGRRYLSDTPAQLPDFVGNGLACRHCHP
GRDGEVGTEANAAPFVGVVGRFPQYSARHGRLITLEQRIGDCFERSLNGR
ALALDHPALIDMLAYMSWLSQGVPVGAVVAGHGIPTLTLEREPDGVHGEA
LYQARCLACHGADGSGTLDADGRYLFPPLWGPRSFNTGAGMNRQATAAGF
IKHGMSLSDEEAWDVAGFVLTHPRPLF

3D structure

• PDB: 4wqe Thiosulfate Dehydrogenase (TsdA) from Allochromatium vinosum: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO THIOSULFATE OXIDATION.
• Chain: A
• Resolution: 1.4 Å

Enzymatic activity

• Enzyme Commision number: 1.8.2.2: thiosulfate dehydrogenase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HEC	A	C49 C52 H53 F69 R92 C96 F97 S100 L101 G137 I138 F189	C45 C48 H49 F65 R88 C92 F93 S96 L97 G133 I134 F185
BS02	HEC	A	H51 C52 R159 C160 C163 H164 F180 P181 P182 L183 F189 F204 I205 M209	H47 C48 R155 C156 C159 H160 F176 P177 P178 L179 F185 F200 I201 M205
BS03	THJ	A	R82 R92 G194	R78 R88 G190
BS04	SO3	A	R82 C96 R99 S100 A193 G194	R78 C92 R95 S96 A189 G190

Gene Ontology

Molecular Function

• GO:0009055 electron transfer activity
• GO:0016491 oxidoreductase activity
• GO:0020037 heme binding
• GO:0046872 metal ion binding
• GO:0050338 thiosulfate dehydrogenase activity

Cellular Component

• GO:0042597 periplasmic space

External links

• PDB: RCSB:4wqe, PDBe:4wqe, PDBj:4wqe
• PDBsum: 4wqe
• PubMed: 25673691
• UniProt: D3RVD4|TSDA_ALLVD Thiosulfate dehydrogenase (Gene Name=tsdA)