Structure of PDB 4wq9 Chain A

Receptor sequence

>4wq9A (length=230) Species: 572477 (Allochromatium vinosum DSM 180)

TVALTVPAAALLPDGALGESIVRGRRYLSDTPAQLPDFVGNGLACRHCHP
GRDGEVGTEANAAPFVGVVGRFPQYSARHGRLITLEQRIGDCFERSLNGR
ALALDHPALIDMLAYMSWLSQGVPVGAVVAGHGIPTLTLEREPDGVHGEA
LYQARCLACHGADGSGTLDADGRYLFPPLWGPRSFNTGAGMNRQATAAGF
IKHKMPLGSLSDEEAWDVAGFVLTHPRPLF

3D structure

• PDB: 4wq9 Thiosulfate Dehydrogenase (TsdA) from Allochromatium vinosum: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO THIOSULFATE OXIDATION.
• Chain: A
• Resolution: 1.47 Å

Enzymatic activity

• Enzyme Commision number: 1.8.2.2: thiosulfate dehydrogenase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HEC	A	C49 C52 H53 F69 R92 A96 F97 S100 L101 G137 I138 F189	C45 C48 H49 F65 R88 A92 F93 S96 L97 G133 I134 F185
BS02	HEC	A	H51 C52 P54 R159 C160 C163 H164 F180 P181 P182 L183 F204 I205 M209 P210 L211	H47 C48 P50 R155 C156 C159 H160 F176 P177 P178 L179 F200 I201 M205 P206 L207
BS03	THJ	A	R82 A96 R99 S100 A193 G194	R78 A92 R95 S96 A189 G190

Gene Ontology

Molecular Function

• GO:0009055 electron transfer activity
• GO:0016491 oxidoreductase activity
• GO:0020037 heme binding
• GO:0046872 metal ion binding
• GO:0050338 thiosulfate dehydrogenase activity

Cellular Component

• GO:0042597 periplasmic space

External links

• PDB: RCSB:4wq9, PDBe:4wq9, PDBj:4wq9
• PDBsum: 4wq9
• PubMed: 25673691
• UniProt: D3RVD4|TSDA_ALLVD Thiosulfate dehydrogenase (Gene Name=tsdA)