Structure of PDB 4wq0 Chain A

Receptor sequence
>4wq0A (length=397) Species: 33903 (Streptomyces avermitilis) [Search protein sequence]
PIAFPFPDPPSVCELPPELAEIRDGQSVVEVKFPDGISGWMVTKHADVRK
VLVDSRFSSKVMATAAAAMSETETGKLMNESLVGMDAPEHTRLRKLVTKA
FTARRVETLRPRITELVGQLLDELETLPRPVDLVKNFSVPLPVRVICELL
GVPAGDQDTFHAWSNALLGDWQQVVEKEAATVSLVNYFGELIAVKRENPA
DDLISELIAISDGDSTLTEREIIALSIGILSAGHETTANQISMFLVTLLH
NPEELDKLRDNREAIPKAVDELLRFVPLTTTGGIIPRLTTAEVELSGGQV
LPAGAVVLPAVATANRDPEVFEDGERLNVTRENNPHLAFGAGIHHCLGAQ
LARIELQEALGAILDRMPQVRLAVPESELRLKSASIIRGLESLPITW
3D structure
PDB4wq0 Crystal structure of cytochrome P450 CYP107W1 from Streptomyces avermitilis in complex with Oligomycin A
ChainA
Resolution2.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) G176 A239 E242 T243 T244 T288 C353 L354 G355 E362 I394
Catalytic site (residue number reindexed from 1) G169 A232 E235 T236 T237 T281 C346 L347 G348 E355 I387
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A L89 V90 H97 R101 F108 G240 T243 I291 R294 A345 F346 H351 C353 L354 G355 L82 V83 H90 R94 F101 G233 T236 I284 R287 A338 F339 H344 C346 L347 G348
BS02 EFO A F11 F40 M69 M76 W178 F4 F33 M62 M69 W171
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 heme binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:4wq0, PDBe:4wq0, PDBj:4wq0
PDBsum4wq0
PubMed
UniProtQ93HJ0

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