Structure of PDB 4wng Chain A

Receptor sequence
>4wngA (length=330) Species: 9606 (Homo sapiens) [Search protein sequence]
GSMEASCLELALEGERLCKSGDCRAGVSFFEAAVQVGTEDLKTLSAIYSQ
LGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGN
FDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGGEFPEEV
RDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIA
HEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQ
LKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDRIGEGRA
CWSLGNAYTALGNHDQAMHFAEKHLEISRE
3D structure
PDB4wng Structural basis for the recognition of the scaffold protein Frmpd4/Preso1 by the TPR domain of the adaptor protein LGN
ChainA
Resolution2.11 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A E25 A56 Q60 N63 F66 Y67 D81 G93 K96 N100 N103 K106 R136 Y139 H146 R196 N200 N203 L207 R221 R235 R236 N240 E15 A46 Q50 N53 F56 Y57 D71 G83 K86 N90 N93 K96 R126 Y129 H136 R179 N183 N186 L190 R204 R218 R219 N223
External links
PDB RCSB:4wng, PDBe:4wng, PDBj:4wng
PDBsum4wng
PubMed25664792
UniProtP81274|GPSM2_HUMAN G-protein-signaling modulator 2 (Gene Name=GPSM2)

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