Structure of PDB 4wnf Chain A

Receptor sequence
>4wnfA (length=255) Species: 9606 (Homo sapiens) [Search protein sequence]
SMEASCLELALEGERLCKSGDCRAGVSFFEAAVQVGTEDLKTLSAIYSQL
GNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGNF
DEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGCPPQDVGE
FPEEVRDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFR
DAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTL
LLARQ
3D structure
PDB4wnf Structural basis for the recognition of the scaffold protein Frmpd4/Preso1 by the TPR domain of the adaptor protein LGN
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A E25 Q60 N63 F66 D81 G93 K96 N100 N103 K106 H121 R136 Y139 H146 R196 N200 N203 Y206 R221 R235 R236 N240 E14 Q49 N52 F55 D70 G82 K85 N89 N92 K95 H110 R125 Y128 H135 R184 N188 N191 Y194 R209 R223 R224 N228
External links
PDB RCSB:4wnf, PDBe:4wnf, PDBj:4wnf
PDBsum4wnf
PubMed25664792
UniProtP81274|GPSM2_HUMAN G-protein-signaling modulator 2 (Gene Name=GPSM2)

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