Structure of PDB 4wlm Chain A

Receptor sequence
>4wlmA (length=286) Species: 10090 (Mus musculus) [Search protein sequence]
PVDYHLLMMFTKAEHNAPLQAKARVALSSLLRLAKFEAHEVLNLHFVSEE
ASREVAKALLRELLFKCKVIFHDVAVLTDKLFPVVEAMQKYFSAYYSDSI
FFLSVAMHQIMPKEIPRIIQLDLDLKYKTNIRELFEEFDNFLPGAVIGIA
REMQPVYRHTFWQFRHENPKTRVGDPPPEGLPGFNSGVMLLNLEAMRQSP
LYSHLLEPSWVQQLADKYHFRGHLGDQDFFTMIGMEHPELFHVLDCTWNR
QLCTWWRDHGYSDVFQAYFRCEGHVKIYHGNCNTPI
3D structure
PDB4wlm Notch-modifying xylosyltransferase structures support an SNi-like retaining mechanism.
ChainA
Resolution3.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.4.2.62: xylosyl alpha-1,3-xylosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D225 D227 H382 D122 D124 H279
Gene Ontology
Molecular Function
GO:0016757 glycosyltransferase activity
GO:0035252 UDP-xylosyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:4wlm, PDBe:4wlm, PDBj:4wlm
PDBsum4wlm
PubMed26414444
UniProtQ3U4G3|XXLT1_MOUSE Xyloside xylosyltransferase 1 (Gene Name=Xxylt1)

[Back to BioLiP]