Structure of PDB 4wk2 Chain A

Receptor sequence
>4wk2A (length=448) Species: 9606 (Homo sapiens) [Search protein sequence]
FNLDAEAPAVLSGPPGSFFGFSVEFYRPGTDGVSVLVGAPKANTSQPGVL
QGGAVYLCPWGAQCTPIEFDSKGSRLLESSLSSEGEEPVEYKSLQWFGAT
VRAHGSSILACAPLYSWRTEKEPLSDPVGTCYLSTDNFTRILEYAPCRSD
FSWAAGQGYCQGGFSAEFTKTGRVVLGGPGSYFWQGQILSATQEQIAESY
YPEYLINLVQGQLQTRQASSIYDDSYLGYSVAVGEFSGDDTEDFVAGVPK
GNLTYGYVTILNGSDIRSLYNFSGEQMASYFGYAVAATDVNGDGLDDLLV
GAPLLMDRTPDGRPQEVGRVYVYLQHPAGIEPTPTLTLTGHDEFGRFGSS
LTPLGDLDQDGYNDVAIGAPFGGETQQGVVFVFPGGPGGLGSKPSQVLQP
LWAASHTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKAVVYRGRPVV
3D structure
PDB4wk2 Metal ion and ligand binding of integrin alpha 5 beta 1.
ChainA
Resolution2.5 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A F187 D227 F183 D223
BS02 MAN A A222 S223 A218 S219
BS03 CA A E239 S241 D243 T245 D247 E235 S237 D239 T241 D243
BS04 CA A D293 N295 D297 L299 D301 D289 N291 D293 L295 D297
BS05 CA A D360 D362 D364 Y366 D368 D356 D358 D360 Y362 D364
BS06 CA A D424 D426 N428 Y430 D432 D420 D422 N424 Y426 D428
Gene Ontology
Cellular Component
GO:0008305 integrin complex

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4wk2, PDBe:4wk2, PDBj:4wk2
PDBsum4wk2
PubMed25475857
UniProtP08648|ITA5_HUMAN Integrin alpha-5 (Gene Name=ITGA5)

[Back to BioLiP]