Structure of PDB 4wjk Chain A

Receptor sequence
>4wjkA (length=452) Species: 9606 (Homo sapiens) [Search protein sequence]
FNLDAEAPAVLSGPPGSFFGFSVEFYRPGTDGVSVLVGAPKANTSQPGVL
QGGAVYLCPWGASPTQCTPIEFDSKGSRLLESSLSSSEGEEPVEYKSLQW
FGATVRAHGSSILACAPLYSWRTEKEPLSDPVGTCYLSTDNFTRILEYAP
CRSDFSWAAGQGYCQGGFSAEFTKTGRVVLGGPGSYFWQGQILSATQEQI
AESYYPEYLINLVQGQLQTRQASSIYDDSYLGYSVAVGEFSGDDTEDFVA
GVPKGNLTYGYVTILNGSDIRSLYNFSGEQMASYFGYAVAATDVNGDGLD
DLLVGAPLLMDRTPDGRPQEVGRVYVYLQHPAGIEPTPTLTLTGHDEFGR
FGSSLTPLGDLDQDGYNDVAIGAPFGGETQQGVVFVFPGGPGGLGSKPSQ
VLQPLWAASHTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKAVVYRGRP
VV
3D structure
PDB4wjk Metal ion and ligand binding of integrin alpha 5 beta 1.
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A E239 S241 D243 T245 D247 E239 S241 D243 T245 D247
BS02 CA A D293 N295 D297 L299 D301 D293 N295 D297 L299 D301
BS03 CA A D360 D362 D364 Y366 D368 D360 D362 D364 Y366 D368
BS04 CA A D424 D426 N428 Y430 D432 D424 D426 N428 Y430 D432
Gene Ontology
Cellular Component
GO:0008305 integrin complex

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Biological Process
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Cellular Component
External links
PDB RCSB:4wjk, PDBe:4wjk, PDBj:4wjk
PDBsum4wjk
PubMed25475857
UniProtP08648|ITA5_HUMAN Integrin alpha-5 (Gene Name=ITGA5)

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