Structure of PDB 4whg Chain A

Receptor sequence
>4whgA (length=234) Species: 9606 (Homo sapiens) [Search protein sequence]
PANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLL
SGSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEG
KLIFCSGLVLHRLQCARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALV
LITDRHGLQEPRRVEELQNRIASCLKEHVAAVAGASCLSRLLGKLPELRT
LCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF
3D structure
PDB4whg Induction of Autophagic Death in Cancer Cells by Agonizing TR3 and Attenuating Akt2 Activity
ChainA
Resolution2.18 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3NB A L178 T182 Q197 L224 L149 T153 Q168 L191
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4whg, PDBe:4whg, PDBj:4whg
PDBsum4whg
PubMed26235054
UniProtP22736|NR4A1_HUMAN Nuclear receptor subfamily 4immunitygroup A member 1 (Gene Name=NR4A1)

[Back to BioLiP]