Structure of PDB 4wfe Chain A

Receptor sequence
>4wfeA (length=253) Species: 9606 (Homo sapiens) [Search protein sequence]
RSTTLLALLALVLLYLVSGALVFRALEQPHEQQAQRELGEVREKFLRAHP
CVSDQELGLLIKEVADALGGGADPETSHSAWDLGSAFFFSGTIITTIGYG
NVALRTDAGRLFCIFYALVGIPLFGILLAGVGDRLGSSLRHGIGHIEAIF
LKWHVPPELVRVLSAMLFLLIGCLLFVLTPTFVFCYMEDWSKLEAIYFVI
VTLTTVGFGDYVAGADPRQDSPAYQPLVWFWILLGLAYFASVLTTIGNWL
RVV
3D structure
PDB4wfe Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A S112 D115 S118 D249 S79 D82 S85 D216
BS02 CA A G98 D100 G71 D73
Gene Ontology
Molecular Function
GO:0005267 potassium channel activity
Biological Process
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4wfe, PDBe:4wfe, PDBj:4wfe
PDBsum4wfe
PubMed25471887
UniProtQ9NYG8|KCNK4_HUMAN Potassium channel subfamily K member 4 (Gene Name=KCNK4)

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