Structure of PDB 4wej Chain A

Receptor sequence
>4wejA (length=500) Species: 652611 (Pseudomonas aeruginosa PA14) [Search protein sequence]
RSVRHIAIPAHRGLITDRNGEPLAVSTPVTTLWANPKELMTAKERWPQLA
AALGQDTKLFADRIEQNAEREFIYLVRGLTPEQGEGVIALKVPGVYSIEE
FRRFYPAGEVVAHAVGFTDVDDRGREGIELAFDEWLAGVPGKRQVLKDRR
GRVIKDVQVTKNAKPGKTLALSIDLRLQYLAHRELRNALLENGAKAGSLV
IMDVKTGEILAMTNQPTYNPNNRRNLQPAAMRNRAMIDVFEPGSTVKPFS
MSAALASGRWKPSDIVDVYPGTLQIGRYTIRDVSRNSRQLDLTGILIKSS
NVGISKIAFDIGAESIYSVMQQVGLGQDTGLGFPGERVGNLPNHRKWPKA
ETATLAYGYGLSVTAIQLAHAYAALANDGKSVPLSMTRVDRVPDGVQVIS
PEVASTVQGMLQQVVEAQGGVFRAQVPGYHAAGKSGTARKNAYRSLFAGF
APATDPRIAMVVVIDEPSKAGYFGGLVSAPVFSKVMAGALRLMNVPPDNL
3D structure
PDB4wej SAR and Structural Analysis of Siderophore-Conjugated Monocarbam Inhibitors of Pseudomonas aeruginosa PBP3.
ChainA
Resolution2.045 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3LB A E291 G293 S294 V333 S334 S349 N351 Y409 G470 S485 G486 T487 A488 R489 Y503 F533 G534 G535 E241 G243 S244 V283 S284 S299 N301 Y359 G420 S435 G436 T437 A438 R439 Y443 F473 G474 G475
Gene Ontology
Molecular Function
GO:0004180 carboxypeptidase activity
GO:0008658 penicillin binding
GO:0008955 peptidoglycan glycosyltransferase activity
Biological Process
GO:0009252 peptidoglycan biosynthetic process
GO:0051301 cell division
GO:0071555 cell wall organization
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4wej, PDBe:4wej, PDBj:4wej
PDBsum4wej
PubMed26005529
UniProtA0A0M3KKZ3

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