Structure of PDB 4wb3 Chain A

Receptor sequence
>4wb3A (length=68) Species: 10090 (Mus musculus) [Search protein sequence]
NLHLLRQKIEEQAAKYKHSVPKKCCYDGARVNFYETCEERVARVTIGPLC
IRAFNECCTIANKIRKES
3D structure
PDB4wb3 Structural basis for the targeting of complement anaphylatoxin C5a using a mixed L-RNA/L-DNA aptamer.
ChainA
Resolution2.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A R684 E688 H696 S697 V698 K700 K701 Y704 D705 R708 F711 R718 R721 V722 T723 I724 R6 E10 H18 S19 V20 K22 K23 Y26 D27 R30 F33 R40 R43 V44 T45 I46
Gene Ontology
Biological Process
GO:0006954 inflammatory response
GO:0006956 complement activation
Cellular Component
GO:0005576 extracellular region

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4wb3, PDBe:4wb3, PDBj:4wb3
PDBsum4wb3
PubMed25901944
UniProtP06684|CO5_MOUSE Complement C5 (Gene Name=C5)

[Back to BioLiP]