Structure of PDB 4wb2 Chain A

Receptor sequence
>4wb2A (length=69) Species: 10090 (Mus musculus) [Search protein sequence]
ANLHLLRQKIEEQAAKYKHSVPKKCCYDGARVNFYETCEERVARVTIGPL
CIRAFNECCTIANKIRKES
3D structure
PDB4wb2 Structural basis for the targeting of complement anaphylatoxin C5a using a mixed L-RNA/L-DNA aptamer.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna A R684 E688 H696 S697 V698 K700 K701 Y704 D705 R708 F711 R718 R721 V722 T723 I724 R7 E11 H19 S20 V21 K23 K24 Y27 D28 R31 F34 R41 R44 V45 T46 I47
Gene Ontology
Biological Process
GO:0006954 inflammatory response
GO:0006956 complement activation
Cellular Component
GO:0005576 extracellular region

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:4wb2, PDBe:4wb2, PDBj:4wb2
PDBsum4wb2
PubMed25901944
UniProtP06684|CO5_MOUSE Complement C5 (Gene Name=C5)

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