Structure of PDB 4wan Chain A

Receptor sequence
>4wanA (length=124) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
PTKFQDKYYIPVDQYPDVNFVGLLLGPRGRTLRKLQEDSNCKIAIRGRGS
VKEGKNASDLPPGAMNFEDPLHCLIIADSEDKIQKGIKVCQNIVIKAVTS
PEGQNDLKRGQLRELAELNGTLRE
3D structure
PDB4wan Structural basis for recognition of intron branchpoint RNA by yeast Msl5 and selective effects of interfacial mutations on splicing of yeast pre-mRNAs.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A V165 G166 L169 G170 P171 R172 G173 L176 R177 K186 I189 R190 K196 P205 E246 G247 N249 K252 R253 Q255 L256 L259 T265 V21 G22 L25 G26 P27 R28 G29 L32 R33 K42 I45 R46 K52 P61 E102 G103 N105 K108 R109 Q111 L112 L115 T121
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:4wan, PDBe:4wan, PDBj:4wan
PDBsum4wan
PubMed25587180
UniProtQ12186|BBP_YEAST Branchpoint-bridging protein (Gene Name=MSL5)

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