Structure of PDB 4wak Chain A

Receptor sequence
>4wakA (length=179) Species: 71421 (Haemophilus influenzae Rd KW20) [Search protein sequence]
TPHYLVIACSDSRVPAEKLTGELFVHRNVANQVIHTDFNCLSVVQYAVDV
LKIEHIIICGHTNCGGIHAAMADKDLGLINNWLLHIRDIWFKHGHLLGKL
SPEKRADMLTKINVAEQVYNLGRTSIVKSAWERGQKLSLHGWVYDVNDGF
LVDQGVMATSRETLEISYRNAIARLSILD
3D structure
PDB4wak Allosteric Reversion of Haemophilus influenzae beta-Carbonic Anhydrase via a Proline Shift.
ChainA
Resolution2.49 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) C42 D44 R46 H98 C101
Catalytic site (residue number reindexed from 1) C9 D11 R13 H61 C64
Enzyme Commision number 4.2.1.1: carbonic anhydrase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C42 D44 H98 C101 C9 D11 H61 C64
BS02 BCT A R160 K165 R198 R123 K128 R161
Gene Ontology
Molecular Function
GO:0004089 carbonate dehydratase activity
GO:0008270 zinc ion binding
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0015976 carbon utilization
Cellular Component
GO:0005575 cellular_component

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Cellular Component
External links
PDB RCSB:4wak, PDBe:4wak, PDBj:4wak
PDBsum4wak
PubMed25506786
UniProtP45148|CAN_HAEIN Carbonic anhydrase 2 (Gene Name=can)

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