Structure of PDB 4waj Chain A

Receptor sequence
>4wajA (length=185) Species: 71421 (Haemophilus influenzae Rd KW20) [Search protein sequence]
QTPHYLWIGCSDSRVSPEKLTNLEPGELFVHRNVANQVIHTDFNCLSVVQ
YAVDVLKIEHIIICGHTNCGGIHAAMADKDLGLINNWLLHIRDIWFKHGH
LLGKLSPEKRADMLTKINVAEQVYNLGRTSIVKSAWERGQKLSLHGWVYD
VNDGFLVDQGVMATSRETLEISYRNAIARLSILDE
3D structure
PDB4waj Allosteric Reversion of Haemophilus influenzae beta-Carbonic Anhydrase via a Proline Shift.
ChainA
Resolution2.7 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) C42 D44 R46 H98 C101
Catalytic site (residue number reindexed from 1) C10 D12 R14 H66 C69
Enzyme Commision number 4.2.1.1: carbonic anhydrase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C42 H98 C101 C10 H66 C69
Gene Ontology
Molecular Function
GO:0004089 carbonate dehydratase activity
GO:0008270 zinc ion binding
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0015976 carbon utilization
Cellular Component
GO:0005575 cellular_component

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4waj, PDBe:4waj, PDBj:4waj
PDBsum4waj
PubMed25506786
UniProtP45148|CAN_HAEIN Carbonic anhydrase 2 (Gene Name=can)

[Back to BioLiP]