Structure of PDB 4w97 Chain A

Receptor sequence
>4w97A (length=196) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
RVAGQVNSRRGELLELAAAMFAERGLRATTVRDIADGAGILSGSLYHHFA
SKEEMVDELLRGFLDWLFARYRDIVDSTANPLERLQGLFMASFEAIEHHH
AQVVIYQDEAQRLASQPRFSYIEDRNKQQRKMWVDVLNQGIEEGYFRPDL
DVDLVYRFIRDTTWVSVRWYRPGGPLTAQQVGQQYLAIVLGGITKE
3D structure
PDB4w97 Structural and Functional Characterization of a Ketosteroid Transcriptional Regulator of Mycobacterium tuberculosis.
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UCA A Y108 Q109 N128 Q131 R159 R162 D163 W166 Y106 Q107 N126 Q129 R157 R160 D161 W164 MOAD: Kd=0.08uM
PDBbind-CN: -logKd/Ki=7.10,Kd=0.08uM
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:4w97, PDBe:4w97, PDBj:4w97
PDBsum4w97
PubMed25406313
UniProtP9WMB9|KSTR2_MYCTU HTH-type transcriptional repressor KstR2 (Gene Name=kstR2)

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