Structure of PDB 4w79 Chain A

Receptor sequence
>4w79A (length=202) Species: 9606 (Homo sapiens) [Search protein sequence]
SEGNGPAAVHYQPASPPRDACVYSSCYCEENVWKLCEYIKNHDQYPLEEC
YAVFISNERKMIPIWKQQARPGDGPVIWDYHVVLLHVSSGGQSFIYDLDT
VLPFPCLFDTYVEDAIKSDDDIHPQFRRKFRVICADSYLKNFASDRSHMK
DSSGNWREPPPPYPCIETGDSKMNLNDFISMDPKVGWGAVYTLSEFTHRF
GS
3D structure
PDB4w79 Crystal structure of human protein N-terminal glutamine amidohydrolase, an initial component of the N-end rule pathway.
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.1.122: protein N-terminal glutamine amidohydrolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CO3 A V132 R199 V132 R199
BS02 CO3 A H42 D43 H42 D43
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008418 protein-N-terminal asparagine amidohydrolase activity
GO:0016787 hydrolase activity
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0070773 protein-N-terminal glutamine amidohydrolase activity
Biological Process
GO:0036211 protein modification process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4w79, PDBe:4w79, PDBj:4w79
PDBsum4w79
PubMed25356641
UniProtQ96HA8|NTAQ1_HUMAN Protein N-terminal glutamine amidohydrolase (Gene Name=NTAQ1)

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