Structure of PDB 4v59 Chain A

Receptor sequence

>4v59A (length=1457) Species: 5541 (Thermomyces lanuginosus)

MRPEVEQELAYTLLVELLAYQFAMPVRWIETQDVILAEKRTERIVEIGPS
DTLGGMARRTLQSKYEAYDAATSVQRQILCYCKDAKEIYYDVEPIDALTK
DQRALFKQQLEIIARYLKMDLRAGDKAFVASQESQKALQAQLDLWQAEHG
DIYAAGIEPAFDPLKARVYDSSWNWARQDALSMYYDIIFGRLRVVDREIV
SQCIQIMNRSNPLLLEFMQYHIDHCPTERGETYQLAKELGQQLIENCKEV
LGKPPVYKDVSIPTGPQTTIDARGNIQYQEVPRASARKFEHYVKQMAEGG
PISQYSNRTKVQNDLRSVYKLIRRQHRLSKSSQLQFNALYKDVIRALAMK
VETIPFLHLRKKDEFGNWEYSKKLTGIYLDGLEAAARSGLTFQGKHALMT
GAGAGSIGAEVLQGLLSGGAKVIVTTSRFSRQVTEYYQGIYARCGARGSQ
LVVVPFNQGSKQDVEALVNYIYDTKNGLGWDLDYVVPFAAIPENGREIDS
IDSKSELAHRIMLTNLLRLLGAIKTQKKERGYETRPAQVILPLSPNHGTF
GNDGLYSESKLALETLFNRWYSESWGNYLTICGAVIGWTRGTGLMSANNL
VAEGVEKLGVRTFSQQEMAFNLLGLMAPAIVNLCQSDPVFADLNGGLQFI
PDLKGLMTKLRKEIMETSAIRQAVIKETAIENKVVNGEDHEALYRRVITE
PRANLKYPFPELPDWDKDIKPLNDQLRGMVNLDKVVVVTGLAEIGPWGNA
RTRWEMEAYGKFSLEGCVEMAWMMGLIKNHNGPLKGKPYSGWVDAKTGEP
VDDKDVKAKYEKYILEHSGIRLIEPELFGGYDPNRKQLLQEVVIEQDLEP
FEASKEQAEEFKREHGDKVEIFEIPETGQYTVRLRKGATLLIPKALQFDR
LVAGQIPTGWDARRYGVPEDIIQQVDPVTLYVLVSVAEALLSSGITDPYE
FYKYVHLSEVGNCIGSGVGGTSALRGMYKDRYLDKPVQKDILQESFVNTM
AAWVNMLLLSSTGPIKTPVGACATAVESLDVGYDTIMQGKARVCLVGGFD
DFQEEGSYEFANMGATSNAKEEFARGREPGEMSRPTSTTRNGFMESQGCG
VQVIMTAQLALEMGVPIYGIVAMTSTATDKIGRSVPAPGQGVLTTAREKS
GNFPSPLLDIKYRRRQLELRRQQIKQWKESEYLYLQEEVAAIKSQRSEED
GPFDETAYLRERTEHIEREARRQEAEAQTSFGNEFWRRDSRIAPLRGALA
TWGLTIDDLGVASFHGTSTVANDKNESDVICQQLKHLGRTKGNAVLGIFQ
KYLTGHPKGAAGAWMLNGCLQVLNTGIVPGNRNADNVDKVMEQFDYIVYP
SRSIKTDGIKAFSVTSFGFGQKGAQAIGVHPKYLFATLDKAQYEAYCVKV
QARQKKAYRFFHNGLINNKLFVAKDKAPYEDRIQSKVFLNPQSRVTQESN
GELKFPA

3D structure

• PDB: 4v59 Structure of Fungal Fatty Acid Synthase and Implications for Iterative Substrate Shuttling
• Chain: A
• Resolution: 3.1 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	NAP	A	G659 I665 T684 S685 R686 N715 Q716 F746 A748 P800 Y814 K818 I844 L852	G401 I407 T426 S427 R428 N457 Q458 F488 A490 P542 Y556 K560 I586 L594

Gene Ontology

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UnboundLocalError

Python 3.6.8: /usr/bin/python3 Tue Dec 3 01:10:05 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1443                 pubmed=display_regular_ligand(pdbid,asym_id,lig3,ligIdx,title)

   1444         else:

=> 1445             pubmed,uniprot=display_protein_receptor(pdbid,asym_id,title)

   1446     

   1447     uniprot_line=''

pubmed = '', uniprot = '', display_protein_receptor = <function display_protein_receptor>, pdbid = '4v59', asym_id = 'A', title = 'Structure of Fungal Fatty Acid Synthase and Implications for Iterative Substrate Shuttling'

 /var/www/html/BioLiP/pdb.cgi in display_protein_receptor(pdbid='4v59', asym_id='A', title='Structure of Fungal Fatty Acid Synthase and Implications for Iterative Substrate Shuttling')

    839 

    840     if go:

=>  841         display_go(go,uniprot,pdbid,asym_id)

    842     return pubmed,uniprot

    843 

global display_go = <function display_go>, go = '0000287,0004312,0004315,0004316,0005835,0006633,0008897,0016746,0042759', uniprot = '', pdbid = '4v59', asym_id = 'A'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0000287,0004312,0004315,0004316,0005835,0006633,0008897,0016746,0042759', uniprot='', pdbid='4v59', asym_id='A')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>