Structure of PDB 4uwx Chain A

Receptor sequence
>4uwxA (length=234) Species: 10090 (Mus musculus) [Search protein sequence]
GSEFSAMMYIQELRSGLRDMHLLSCLESLRVSLNNNPVSWVQTFGAEGLA
SLLDILKRLHDEKGNYDSRNQHEIIRCLKAFMNNKFGIKTMLETEEGILL
LVRAMDPAVPNMMIDAAKLLSALCILPQPEDMNERVLEAMTERAEMDEVE
RFQPLLDGLKSGTSIALKVGCLQLINALITPAEELDFRVHIRSELMRLGL
HQVLQELREIENEDMKVQLCVFDEQGDEDFFDLK
3D structure
PDB4uwx Structural and Biochemical Basis for the Inhibitory Effect of Liprin-Alpha3 on Mouse Diaphanous 1 (Mdia1) Function.
ChainA
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A K252 I259 Q307 N310 A311 T314 P315 E317 V355 E358 Q359 E362 K118 I125 Q173 N176 A177 T180 P181 E183 V221 E224 Q225 E228
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0031267 small GTPase binding
Biological Process
GO:0016043 cellular component organization
GO:0030036 actin cytoskeleton organization

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Molecular Function
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Biological Process
External links
PDB RCSB:4uwx, PDBe:4uwx, PDBj:4uwx
PDBsum4uwx
PubMed25911102
UniProtO08808|DIAP1_MOUSE Protein diaphanous homolog 1 (Gene Name=Diaph1)

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