Structure of PDB 4uwh Chain A |
>4uwhA (length=554) Species: 9606 (Homo sapiens) [Search protein sequence] |
DLKPNAATRDQLNIIVSYPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFL KCVNWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRRYAVARL RQADDEDLLMYLLQLVQALKYENFDDIKNGLEPINSAEIDSSQIITSPLP NLEQDLCTFLISRACKNSTLANYLYWYVIVECEDQDTQQRDPKTHEMYLN VMRRFSQALLKGDKSVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKK NERLQALLGDNEKMNLSDVELIPLPLEPQVKIRGIIPETATLFKSALMPA QLFFKTEDGGKYPVIFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTP YKVLATSTKHGFMQFIQSVPVAEVLDTEGSIQNFFRKYAPSENGPNGISA EVMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILGRD PKPLPPPMKLNKEMVEGMGGTQSEQYQEFRKQCYTAFLHLRRYSNLILNL FSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQSLIDESVHA LFAA |
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PDB | 4uwh Discovery of (2S)-8-[(3R)-3-Methylmorpholin-4-Yl]-1-(3-Methyl-2-Oxo-Butyl)-2-(Trifluoromethyl)-3,4-Dihydro-2H-Pyrimido[1,2-A]Pyrimidin-6-One: A Novel Potent and Selective Inhibitor of Vps34 for the Treatment of Solid Tumors. |
Chain | A |
Resolution | 1.93 Å |
3D structure |
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Enzyme Commision number |
2.7.1.137: phosphatidylinositol 3-kinase. |
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