Structure of PDB 4uuv Chain A

Receptor sequence
>4uuvA (length=96) Species: 9606 (Homo sapiens) [Search protein sequence]
GALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRP
AMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPDALFSMAFPD
3D structure
PDB4uuv Structures of the Ets Domains of Transcription Factors Etv1, Etv4, Etv5 and Fev: Determinants of DNA Binding and Redox Regulation by Disulfide Bond Formation.
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A Y392 R397 R400 Y403 K410 R415 Y416 Y54 R59 R62 Y65 K72 R77 Y78
BS02 dna A Q342 L343 W381 K385 R387 D393 K394 S398 Y401 Y402 Q4 L5 W43 K47 R49 D55 K56 S60 Y63 Y64
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:4uuv, PDBe:4uuv, PDBj:4uuv
PDBsum4uuv
PubMed25866208
UniProtP43268|ETV4_HUMAN ETS translocation variant 4 (Gene Name=ETV4)

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