Structure of PDB 4us3 Chain A

Receptor sequence
>4us3A (length=441) Species: 272558 (Halalkalibacterium halodurans C-125) [Search protein sequence]
GREQWASRLGFILAAMGSAVGLGNIWRFSYVTGENGGAAFLLVYLGFIAL
IGIPIVLAEFTIGRRAQSDAVGSFEKLAPGKPWKVAGLMGVAAGFLILSF
YGVIAGWILFYLFNYITGQLWSAPAEGFGGFFEGFIANPTLPLFWQALFM
IATIWIVAIGVKKGIERSNKILMPLLGVLLIALAIYSLTLGGAKEGLAFL
FSPDWSALKDPGVYLAAISQAFFTLSLGMGALITYGSYVSKDSRLPGAAV
SVAGLDTAFAIIAGIMIFPAVFALGLSPSGGPGLVFVVLPDIFDSIRLGP
IVGIAFFILLGAAALSSAVSLLEVPVAYFMRKFDWSRKQAAITLGVIITL
LGIPSSLSFGVLGEVTIIPGLNIFDSVDFIASSVFLPLGGMIIALFIGWG
WKTSDALAESDLTDSVWGKLWILSLRFIAPIAILIVFLSAF
3D structure
PDB4us3 A Mechanism for Intracellular Release of Na+ by Neurotransmitter/Sodium Symporters
ChainA
Resolution2.098 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TRP A S25 A26 L29 G30 Y108 F230 T231 S233 M236 S327 L328 S18 A19 L22 G23 Y101 F223 T224 S226 M229 S320 L321 MOAD: Kd=4.8uM
PDBbind-CN: -logKd/Ki=5.32,Kd=4.8uM
BS02 NA A G24 V27 G28 A320 S323 S324 G17 V20 G21 A313 S316 S317
BS03 NA A A26 V27 N31 T231 D263 A19 V20 N24 T224 D256
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:4us3, PDBe:4us3, PDBj:4us3
PDBsum4us3
PubMed25282149
UniProtQ9KDT3

[Back to BioLiP]